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Bronx, New York Human Radiation EXDOriments Identification, I . Diagnostic and therapeutic Us8 of tracer doses of mdiuisotopes. Developrneni studies of d3gnostic uses of isotopes and to elucidate abnormal metabolism. 2. Bronx VA Medical Center, Radioisotope Unit (1947 to 1979) and Metabolic Ward, early Ernest Schwartr, M.D., Metabolic Ward. 4. Veterans Administration. No other agency involved. 5 . Subjects: A srnsll number of n o n a l volunteers participated in some studies (307). The l l q e majority, probably several hundred over the years, were patients, either hospitalized or. a s outpatients. All where eligible veterans. Approximate racial mixture: 40% Black, 40% Hispanic, and 20% Caucasian. This distribution Is characteristic of our patient population. &vailable Information, at best, may comprise several names of partijpants in one study. All c!her records are not avetlable. Studies: Thyroid fundion tests, blood flow In pedide gmffs, bone calcium turnover in response to estrogen therapy, plasma protein and insulin turnover, and glucose kinetim. (*!qfe.Or. Yalow has tubmiffed fo VACO reprints of published repods of these studies) L dses varied from 1 microcurie lo 200 microcuries. (B) Isotopes were administered for therapy (leukemia, polycythemia, etc.) but these were not primarily fasearch. (C) Other Research: Clinically indicated diagnostic procedures were off en combined with add-on research components. The research component might be for the purposes of developing an improved test or to better understand ths disease process or a therapeutic modality.
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8 ) kesearch Building: Room 1F-Olc. Locked Office, Several radioisotope unlt C ) Or. Ernest Schwertz: No records wailable from bone kinetics stubies:. Records consist of publicafionsIn the medical literature, minutes of cornmiltee meetings, local hospital and VACO actions and requirements. general descriptions and repods of types of studies condudad and numbers of tests performed, medical review artlcles, and several research protocols. Several bookcases and file ceblneb contain 9. Classification: No documents are classified.