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Director, Rad latlon Laboratory Un lt emit j of Callfornls I have attempted t o susamarlre our art lv ltl erat Crocker Iaboratol‘~ rbce the inception of the @&attan Ro J ect and ite rubrequaat t moi br dlvldfrg py. remarks i n t o hro msln catsgorles, namely the b1OlOglcal ahd Blologlcal nnd llcdlcal Progmm (1) n orl of i Product and Related Wstabollc Btudles. Quits de tall ed mtabollo f studlei have been done vhlch now oakace practically the entln! perloblc Very detailed rtudles wen mbe with plutanlun and other mmbarr of tbs In this elperlmontal wo*, lata hnve been largely employed. M n g tbs d e b secured we- of connlderable value in pladlctlng the mamltude of potentlal hazards o f there rubetancar should they gain entry l n t o the body. metof the work at that tlm, vhlch involved a 6tudJ of the firrim products praduced 1~ abuntlaace of over one percent and having half-line xnnglng fma veekr to yeare, hsr now been publlohod. rM ler with the act ln l de elemento hats appmred i n the open lltenturb. aod ths act ln l de elements, not abl ~plutonium, does pmaent a pots nti al hsaltb bszald; much work was done in thla flsld and the wo* her I l k ~ l a ebarn 0mrlred In a lather ler nya rtl cle. Aeroeol rt die e. mils to the fec t that the inhalation of fiorian produotr~ : t o In h i & ewrg part t clo
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Recently R moet prumfelng pro ced ~ mher been developed whtch employe 0,' jAutmlum and yttrlm, the latter abl rly reprsrentatlve .smber of the booe sceklrg fleslon producte, Py almost n factor of 20. to be proheble, tbere l e tbe lrnaasdlete appllcatlon of de tad n lng moma c cura b4, ra;tdly and Isr lees expensively, the rke let al content of plutonium in lndlrldualr exposed to tbat elesment. served with the fieaton products. mould thle occur, whlch ve belleve It la also probable that the ram effect would IM obIt would be nobd thst In Oe ater lal outlined above that tbe dimetiof effort ? a pr1mor:ly that of protactLon to thee vho el the r -7 be u~rking in 4-19 under Atwic Eaergg Canmleslon rupport o r superrlslon, O r to hrgr nrrmbera af indlrlduale who might be expored to flralon p r o d u b mnb lrradlat*d the firsion of comldenrble qo a ntl ties of either pluto nim or uraclim, or 'both. peace tia spplicatlons of nuclear emra ou bl de thme rsglons vitb vhlch tbs Atpplc aero Comalorion ham dlmct concern. (5) Duuring the pait mar, S. John 2. Bovelr, iom rly Deputy Dllrctor of thr extended oerlcs of expsrlmnts rn rats to d e t e d o s the ahlf't of rodla .rd i r now b ~ n gdmvn up in fin elf om for publicstiao, 4 the rout alan l fl8aat rar let lon in cor rent mt lm in tho rarioue tia mee do mr folla~ing1nadi.tioo. radloelemmt 1s the hear lest of tbe halogsn rerler, lylw balm iodbe, .ad l r now c a p 1 a M vhlch has given ur infooration concernla& tbe anpacity of thli stark1 to produce inJurj in not onl7 the tbyrold, but otber organa and tire use was Im ntl ve befoore ve can ettswt to explom it. elin leal applloatlao & tbe 'Ihe p a t eW3 y a m ham been a lnrm Ohare of our effort Qerobd Um mtaThio V ~ Dnot o n 4 of internst academlcally, but
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them :D n msrled spec lc ~difference in 1LA effect on the thyrold, both n s I C nccamulatlon find degree of deetruct'Lvencee for flven emountr 9f nccumulntlm. ?he prlncfyel arll & l s employed hove been mtn and monkep. .in uP uk lef h cta at ht & doee levels have been obfierved, but ep ce doee not z f the l sc ril ~ s lgland inthe mt for uhlch there l e no ready explanetton, lhln h 9 e not been obecrvcd In the monkey ond proeumblr would not Wke place I n mn, uh!ch doee not suggest t b e t the uee of a l e rsdloelementgfuld not be emplopd thoee cello vhlch a n producing exceea:te amormb Of tha hormone, thJroXim, d leave rsl at lv ely nom1cell at bat em adJscent uninjured. The other methods of therapy for this thyroid dieorder, notably nurgery, x-ray, and more recently, mdlo-iodine, do not poeeees thie unique qu ali fl cat lon. that a ets tl nele not eat fe is c tory, nnd eo a t this point no pnullctlon -7 be only actual trial can eeteblleh uhether Itle uaefW. o r valuelere. l a bi*leC, I t hrin her, obnerved thpt A niimber of vary me theoretical pos albi lit y of the uee of Atin humn hp perth ~ idlsn Its poeslble value In thyrold cancer iole es attractive,but here ngain (7) Bur mombere fmm the pup pr tic lps ted in tbe Bikini operstionr. Included setting up a laboratory on the USB Baron for 4eteXmlning the clmmcter of rs d los c tl re contAIf&netlon tbat took place lonowing the b o dbtoaatlme. Aftsr the de water burnt, eerfoue contamination of the task foorce ve on le vae obeerreb and it f e l l upon thie group to nocertain l t ~cause vhich wao f& to be ths raeult of firsion producto baing accurilatsd in the pLsnkton which MI eubsequently dravn ink tbs ralt water eye tam of the veseele lsavlng tba tlan, the ent ln tank force MI moved to mother a m of Bikini Iagoon to prevent further contarimtlon vhich in rhipr had almdy see& a rather rerime t)ubsequently, our group wae requsstsd by the Aarf thmugb nppropriata cbannelr tD deviae msthoda of dceontemiaatian of these meeele. Concomitant l ~ , the l st lon al Dofinre Radiation & bora to ~war belag o r ~ i z daod est up 8 t Eu a bla Point. A t this tils, ve trained five of their pr~tmnelwhich W m *e nucleue of thio n w extanmire and important ertabliehmnt. In adb ltl m, attbr o ~ era lof w, particularly Dt. 8cott nab weelf, wao opent in con rul bt la via arlelng holl the practical application of the deemtamination procad~mrwed on (8) TO &to, a grsdusta a d 18 uadergraduate otudents ~ O T Obeen tminsd in tbie bborstory in the use of tmcer tschniquee and the handling of rad lmc tim mtmre eel re their dopes, nnd fl ml ly there amI mrabsr vho am currsntly work lLI8 Lbsy hare moved on to take other poaitione, otbere either hsrs or rill
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tom cel ro their doctors b In fl el dr ouch or blophyrlcr, blocheraletry, an& p40101ogy. xn raaitian, % have been tmined ea t e c b n ~ a m ,moas hove moved on to take other paeitionr, ana otherr hare dropped out to become mmled o r eecure different OCC Up at ~ OM. In any emt, thlr Qoer repmeant am reno lr
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8 LELEY: RABI ATION LAI ORATOR I Space doer not porn1 t M elnboza tlm of the mrry rervlcer thlr mwhlno ham period for n lor@ number of act lr lt ler, 0- rubject ta de chr r lil cat lm, others o r yet not. However, it mlght be pertinent to l l r t a feu of the rather l nter oat i ~projecb that have been d e poerlble by the we of this lnstxuwnt. of amerlclum nnd curlm. %e dlrcorery of berkellrnn and callforntrnn vor clad0 porrlble by tbe boPbardnmt ldeatlfled ea o moult of the UK of the &-Inch cfclotran. Am lldlcabd abors, w l l over 100 mw tadlolrotoper b m been p~‘d=Od ud
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