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Dr. Edvard Sil bent e in kao cia f4 Dlnctor ,Thank you for agrwinp t o met with the Fa cUt y Comictoe OQ Research ' urlier, I would appraciatm i t i f you vould bo available in your deprrtPaPt m dIv ill phoj. you dam we are finiehed vith the first proporal so that you do not have to vmtm ti# waiting. & tho COIIIPittee w i l l ba meeting on anothor propomol The CQaPittoe doe8 have a number of quostlon8 and would app tec iata it if you could roply t o thl. in vr it ing befora the meetlne BO that it will be 8nFlrblo for r tud y m du ill, eharafon, up td it c our session. II. you may k n w , t h i 8 whole mtudy of Ttterapauti~:Effect of Total ibdy Ir radi at imvu given only ?mvfeionsl bproval F.y the Faculty Cornittoe on Remearcb in 1967. It i o for thi. reasou then chat X tlrtnk t h a t it ohould be completely ra-evalurrted and a ful low proporal eu brit ted. This study ham bean on-going tota nunrber of yurt ~POW and w. are :old that 70 patient8 have recalved Irradiation and that tLa clinical courao h u parmllod t!tat of comparable pati auto treated with other agenm. Iho in wm ti gators rafer t o Ytutocols Amd Bin this raepect. "hey aleo rofer to Protocol C in regard t o the Iauna Studice. tocolm warm with da application. -port otb data of the 70 pot iu it at roa ted so far. are given io detail u vel1 as certain tests8 but It la not c lou if urrw vi11 be given t o a11 the pati anta in the group re cd ving it im redi at ely 4ft.r it rdi ation 80 l a impliad in thl paragrapn a t the bottom of p8gm 4 or vh ether it xi11 be given cmly prn for alow blood coutt. The anmittae ra que tra full pro mar Exactly har will Palliation be measured? VI11 this be by prripharal Whon will tho r to rod bare marrow be s dai oi ~ terad7Timas of blood COID~O
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tar pnroaat-day us@. It is r t ~ gerto dthat tlun ahodd br NO (2) canseat form -- m e for patiant:. havlns tot81 body ir+&di8tia, . a d anstbat for tii-• havias the ban. ~ t r wtransplant. of Lbwe tho actual benefits, hatarb, etc., should he li sud in far mor. &tali and i n mrdtnu that thr pnticrat UI fully uademtand. 7) It 1s nokld rhrt the referencns ueall fairly ancient; ft would apwar that them nuat ha litrratrito rof*rarrorr t h a t ai. wrh mete