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Machine-read from the scan, so expect some errors. Lines that couldn’t be read are left out.
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FROM : Carroll L. Rrilson, General Xanager SUBJiCT: Meeting of the Advisory Committee for Biology and Medicine The eighth meeting of the Advisory Committee for Biology and Eedicine will be held April 23-24, 1948 at the University of California, Invitation is cordially extended to attend this meeting, 1, Consideration of the l.linutes ofthe meeting o f I2arch 13, 1948. 2. Report on the Fellowship Training Program Homer W. Smith, Chairman, Professor of Physiology and . Director of Physiological Laboratories, New York University College, of Xedicine, New York, 11. Y. Austin M. Brues, Associate Professor of IAedicine, University of Chicago,. Chicago, Illinois. University, Nashville, Tem es see. Hymer Louis Friedel l,Professor of iiadiology, Yestern Reserve University, Cleveland, Ohio. Joseph G. liamilton, Assistant Professor of Medicine and Radiology, URiversity of California, Berkeley, Calif. soy 2. Eracke, Dean, School of Xedicine, University of A 1abana, Bir min gham, A 1a b ama .
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Douglas " hit aker, Chaii-man; Professor of Biology, fir <' Stanford University, m d Dean o f School of Biological ?& Sciences, Stanford University, California. Sric G. Ball, Professor of Biochemistry, Harvard Medical School, Boston, Ilassachusetts. J. H. Bodine, Professor o f Zoalogy, University of Iowa, Iowa City, Iowa. and Director of School of Tharmacy, University of Michigan, Ann Arbor, idichigan, biology and Biophysics, University of Chicago, (3)Postdoctoral Fellowships i n --S ic logical and Agricultural R. F. Gustavson, Chairman; Chancellor of University of Xebraska, Lincoln, Xebraska. i Research Foundation, University of Pernsylvania, G. Evelyn Hutchinson, Professor of Zoology, Yale University, Sew Haven, Connecticut. sity, and Director of Mew York Botznical Gardens, -B. Grants ?lade t o Training Centers (a) Boaman Weke Forest on Crlz Form tion of Tissue Phospholipides" for
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Bo;man Gray School of IJedicine, Xake Forest and Turnover of Sodium and Pots siu min Acute Infections " for one yuar beginning July 1, "Measurement of Volume of Flow of Blood i n the Eidney and Level o f a n Unanesthctized Man by Mer.ns of Radio isotopic Procedure - $5,000 Relaxin Extract of Corpora Lutea on Blood and PC. Summer Courses. for Instructors Ozk Ridge kt ional h.b oratories - I n August 1948 D. Training c t Columbia University in Bio:>hysics There is a possibility tl xt additional needed spxe may be provided by alterations in an existing building now being used largely for storage pur pos ~ s . The matter will be explored further by Dr. G. Fail la. It i s believed that facilities cm be provided without additional all oca - tion of funds t o make possible the training of a substantial numtjcr of fellows in this importnnt field. //.3I tis recomncnded th?.t Dr.Fail la be encouraged t o i develop these training facilities. 3. Presentation of Prosram Outlines by Drs. J, G. Hamilton, John 9. Lmrcnce and Robcrt s. Stone.
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4. Report on Support o f Research Projects Individual Cells in Available Body Secretions, i.e. Oral and Vaginal, o f Animals Subjected t o Deep Therapy X-rays" effects of Radiation from Excessive Amolmt o f 1-131 i n the Organism, and Various Physiological Fhenomena and of Dyspnea and Disability inPatients with Chronic 5. Research Projects for Committee Consideration "Radiomedicine Research": A total of $104,250 was included under this title in a IJassachusetts Institute of Technology general request for funds to Office of Naval Research, amounting to about $1,000,000. has referred this part of the request to the Atomic Energy Commission, Division o f Biology and Ebdicine. The Office of Naval Research refers to work with radioisotopes, (ziric, iron,iodine, sodium, and radiun). Health Service and Atomic hsrgy Commission). patrick of the Office of Haval Resaarch will look into There is a question as t o how much I/",&<r'"''
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this matter and no recommendrLtion i s made at this time. The amoxnt requested is $66,500. Part 11, under Dr. J. G. Trump, refers to (1) Cancer treatment,(2)B act eric i dal effects, and (3) Cathode rzy induced chemical and physical reactions. The total amount should not be divorced from hospital facilities, which a t present are not available at Mass xh use tt s Institute of It is felt that cancer treatment The work on the b act eric i dal effects of X-rays and cathode rays is of interest to the Division of Biology It i s recommended th2.t $15,000 be made avail zb leto the Office of ?Java1 Research for support of %he part of Dr. Trump's program rel c ting to the b act eric i dal effects of X-rcys and cathode rays and closely related problems. Clinical Investigation upon Various Aspacts o f Chronic Pulmonary Disease I hn if este d by Persons Associated with the Industrial Production 2nd Use of Beryllium and its The Trudznu Found:tion is correlating its research work with that of the Un ivor s it y of Rochester group i n the ficld of' beryllium poisoning. The approach at Sr-ranac i s
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largely concerned with the development of the dist u= - sein its chronic form inthe experimental animals. This i s of major importance E$ there has asyet been no development of the chronic form of the disease in a large number of species treated with beryllium alone. Dr.Vor m lds research will involve synergistic effects of lung irri - tants and lung infections with bzryllium. The problem is still one of mnjor importance tothe Commission,+ This project has not yet been completely clarified,but it i s owing tothe overlapping of the Office of s ~ ,va lResearch grants in aid and some phases of the projected research. Dr.Shilling,Dr. Vorwald and Iz rare solving this point, It i s recommended that the research pro j act of the Trudeau Found - tion on beryllium poisoning be approved i n principle subject to final clarification by the Division of Bio loa and Medicine and the Office of Naval Research, Rapid progross i s being mndc in this Liold. Apael has been consisting of E. 9. Lnvronce, Iwill be in wry close touch with this. Hnmilton, St nf ford The Military Liaison Committee xi11 zppoint a group of
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represent z t ives to the panel. of the Chemical Corps c t Chicago isto be continued for several months, particularly for aerosol work, until such time as the panel has evolved a definite program. liaison is being maintained with the Chemical Corps. will probably be Chairman ofthe Panel. 1dc&an will be the twenty-five million curies per square mile will be required t o render an area untenable for periods over one o r two It is estimated that approximately I h - , R. J. Bopley has been appointed as Director of the carried on. Colonel Boers has been the liaison with us. Atomic Energy Commission has expressed interest in this field and expressed their willingness to help, zn t ional mesting of the various interested agencies i s Th,? organization of this unit is being The American Medical Association is developing its plans rapidly. The research program ofDr.St sy ford '%-i-en atthe Universi+,y of Cdi for nia, Los h.geles, has been carefully
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and tothe Manager of Santz Fe Directed Operations. tothe Division of Biology and Medicine car of ul study it was felt thc.t the budget proposed by Br. Varren of $1,250,000 w2.s not realistic in light of the limited physical facilities rv nil able. budget was therefore reduced t o $700,000 with the expectation that the range o f expenditure would probably increase during the year reaching a permanent leva1of expenditure visualized at about ona m d one quarter million dollars The opa rating It is be liev zd ti at this reduction will make no impairment inthc progrnm. In addition, approximctcly $200,000 i n government supplies will be cvailable. The dangcrous lev21 of radiation no longcr exists at the Trinity Site. wire fence placed around the site. The guards h:va bcen ramovod and ahigh The Army is taking over the entire area fura bombing range so no special security will bc indicated.Dr.Stafford Warren proposcts are survey of the sits this summer and r.n allotment of $71,000 for the - cost cnt xi led has bean recommended, It i s recommondcd that one of the smallor sized betatrons,fac il it is s ,for its housing and cn in cl quarters be
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approved investigators of St cn ford Medical School o f Medicine and University of California S Year 1949 - $lC)OJOOO,/further allocation of funds t o depend upon the rscommcndtion of the Committee. This is to be y-. of the Bikini Area and an initial survey area is of great biological importance. Dr. Donaldson of the University of Xnshington hr.s gotten 2‘ 2 group together for this. Arrangements are being made It is estimated that the cost involvzd will bc approxi7. Iieport on Isotope Distribution Thus far Dr. kebs.rsold has encountered no difficulty with the free isotope distribution and believes that 8. Scientific Exhibit at R.lk and for &ikS .A. Sc is nti fic Exhibit for AIM A scientific exhibit for the Am3ricF.n Medical Association mccting and for the Ccntenary mm ting of the Aiwrican bs soci c tion for the Advanccnent of Scionce i s believed an excellent cducationc.1 opportunity for the Atonic Enera Commission to call to the at to nti on of the
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medical profession and other teachers of science its interests and resp on $ ibi li ties.The Public Information Section ,of the Atomic Energy Commission, The Argonne National The Oak Ridge National Laboratory, the Research Division and this Division are cooperating inthe development of such Suggestions as to content are requested. 9. Atomic Casualty Commission The program i n Japan i s developing i n good shape. There are a fair number of competent Ni sei available who are much in t crested in obtaining positions.In addition, competent investigators are being obtained both on n short ,and a longer bzsis. Construction of units to fcxilitatc: th2. study ds being begun c t Hiroshima and a t Kure. k budget of $1,850,000 for Fiscal Year 1948, 1949, and $1,800,000 for Ye?r 1950. It i s plnnned that this program can level when the construction phases are completed. Good coopers tion is still being obtained from the Jzpancse. 10. Report t o the Chairman,Division of Medical Sciences, Mntional 11. Mouse Genetics Progrnm Location of t.lous ~Genetics Colony a t Ozk Ridge - The comments of the Committee on the accompmying r sport nnd m y rncmornndum dnted April 8, 1948 toDr. Holland vi11 be apprcci2tcd.
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The\Lrecommcndations of the Cormti ttee hzve been transmitted tothe staff a t Brookhaven and to thc Office of lJem.,York Dircctcd Operations. Dr. Van Sly ke is taking an active interest ' inthe Brookhcven program and this will mzke fora material strengthening of it. The funds for construction have not been reduced as wc wish t o develop anple facilities both for the Y brookhzven group and for gua st investigators.. The psrsonne3 \_I \i n bio loo has been Erozen at a level of 24 in the scientific can be accommodated a s soon as f z c ili ties are available. This assumes that20or more visiting investigators total personnel in bio loa of rbout 48 is envisaged..Dr.Nims accepts this program. $438,000 with emphasis plac zd on the fact that a considarable share of this is to be used for guest investigators, His oper r ting budget has been setat hoped too btc in a competent mediccl director shortly and a total medical group of 10 i s planned. lit present 15 bed are avcilrtble in the hospital. It i s planncd t o expand this t o /b ring the nw nb ~ rof beds up t o 42 in the next few months. Ultramicrotome for the Sectioning of Bone13. The Custom Scientific Instruments, Inc,, o f hrlington,New Jersey, is interested in developing a microtome that can cut sections of undo calcified bone one quarter inch in diameter and 5 microns o r less thick, They imuld need five toten
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thousand dollars for preliminary exploration and fifteen t o twenty thousand dollars to produce the first model o f such an apparatus. Does the Committee feel this wu ld be useful and worth the expense? Place and time of ?bay Meeting of the Advisory Committee for Biology and Medicine: