Supplemental Agreement Contract No. at-(40-1)-1302 (Redacted)

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Tulane University of SUPPLEMENTAL A OR EW NT THIS SUP~YENTALA m , entered into this day of A 9 1958, by and between the UNITED STATES OF AHERICA (here in after r0ovemmentfl), represented herein by the U N m STATES ATOMIC ENEIZOY COWISSION inafter called the "Contractor*); WHEREAS, the Oovernment and the Contractor entered into Contract lo. AT- {&0-1)-1302, dated June 29, 1951, providing f o r a study of the inilwnco of radiation injury upon physiology of serum lipid8with put i cul ur roference t o the function of the liver) and VHHUW, the Contract has been mended heretofore by Modi4icatioM loa. WHEREhB, the Commission deslrea t o Frovide additional time for coq let ion of the research described in TITLE V I .of Appendix uAm, without additional fundr, to obtain reports thereon, and to effect certain other changes as.re hereinafter more particularly deacribed; and 'IMWEILS, t h i s Supplemental Agreement is authorized by and oxecutod undor t h e Atomic -%y Act of 19s&; Nbll, THERElrORE, the parties hereto do mutually agree that said contract 5.8 hereby modified i n the following particulars, but in no other ar - 1. The following n m uection W5.R is added to Article I: *s. The Contractor s h a l l commence the work 08 soon as feasible, prosecute it with due diligence and submit the reports required hereunder a8 early a s practicable, and not later than the dates specified in Appendix W." 2 . The heeding of Article I1 is changed from V W OF CONTRACTM t o ~SClEDULV,and the follouing new section R7.fl is added t o Article 111 "7. The period during which the work under t h i s contract m y be coducted is hereby extended t o April 30, 1959.R 3. I n subsection 1. f . of Article 111, delete the words "for the sixth period of prformancefl, and the word8 Rat t h e end of the ri xth rid of

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&. Subsection 2. a. of Article 111 is revised to read as follow at *a. On or before the date of commencement of the work on the project described i n Appendix RAn, the Government shell pay tothe Contractor upon submission by the Contractor of a properly certified voucher, b5 per cent of the agreed consideration; provided, hmemr,that this payment shall be reduced by the amount of t h e balance, if any, agreed t o be remaining unexpended from provious work under this contract. m 5.In subsection 2. c . of Article 111, delete the word "term. and substitute therefor the word brorkn. 6. Section 3. of Article In is revised to read a6 follows; m e n renewal of the contract i s desired, the Contractor shall subd t t o the Commission's Oak Ridge Operations Office a renewal proposal as outlined negotiate as tothe amounts each rill contribute for the additional rebearch act iv i - ties t o be conducted, taking into consideration the actual costs incurred for the current work In comparison w i t h the cost estimotes in t h e contract, and, upon agreement, shall execute a formal modification of the contract.* ai.Appendix "Cn attached hereto. The Contractor and the Commission s h a l l then 7. I n TITLE VI of Appendix delete t h e dates nMay 1, 1956 - April 30, 8. I n the introductory paragraph of TITLE VI of Appendix " AW, delete the word8 afar the sixth period of performance.w 9.In subsection 2. a. of TITLE VI of Appendix delete the words *for the - 10. I n subsection 2. b. of T I T I 3 VI of Appendix "AM, delete ths words aduring 11. Paragraph 2. Publications of Appendix lrBw is revised to read a8 followa: * I t is intended that the Contractor ahall have full freedom of publication of the resulta of the research under this contract and the Contractor is urged t o disseminate the results of the =ark through customary scientific publicotion channels, except that ' restricted data' a6 defined in the Atomic Energy Act of 1954 shall be governed by the provisions of Paragraph 3. of this Appendix RBW. t%mever, i n order t o insure that the public disclosure of w ch results will not adversely affect the patent interests of the Government provided I n Paragraph 1, of this Appendix *V entitled ' Patents ' approval for such release shall be secured from the CornisEdon prior t o any such publication.

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" All publications L..a 1 nclude a referen-8 that the result w or developed under a Commission sponsored project. " attached here to and made a part hereof i3 substituted therefor. 12. Appendix nCn is deleted i n its entirety and the new Appendix WITNESS WHEREOF, the parties hereto ham executed this Supplemer,tal Weement t h e day and year first above written. UNITED STATES OF AMERICA BYt UNITED STATES ATOMIC ENERGY COMMISSION EERW M. ROTH, DIRECTOR Rew Orleans. La. ACCEPTANCE BY SENICR INVESTIOATCA I have read the foregoing Supplemental Agreement and the Appendix V a attached 0 h e r e t o and made a part hereof and agree t o be bound by the provisions of this docu-

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(FOR DIRECT AEC RESEARCH CONTMCTS) and scope with submittal date b. Complete Scientific Report On contract- expiration or six 6. Brief reports or manuscripts m a 7 be submitted as desired b y..-_I - - A11 of the above should be addressed t o : Research and Development Division Oak Ridge Operations Office Post Office Box E Oak Ridge, Tennessee er ogress report should briefly describe the scope of investigations undertaken and the significant results obtaimd. between the actual level of activity (expressed i n the various categories of man-onths, facilities procured, travel performed, etc.) and that contemplated i n the contract. Technical reports and articles prepared for publication should be listed wii & bib lio - material contained there in need not be duplicated i n the report. It aou ld also explain any sigmficant differences Reprints or pre prints of all such material should be appended and Renewal proposals, if any, should accmpany the progress r e p o r t and should contain the tyx of information outlined below unless the information i s already contained i n earlier proposals or i n the accompanying progress report. program o r scope for the additional work shouid be clearly explained and the cost estimated should be based upon past experience. Any contemplated change i n

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Title of the project. The institution and department i n which the work will be done. Scientific background including literature relevant t o the proposal, the significance, and t h e motivation. work already In progress the exbent of present support should be stated identifying amounts received from federal agencies. If the proposal is f o r continuation of Scientific scow of the proposed research, its objectives, its relation t o oresent knowledge and t o comparable work Fn progress elsewhere, and a plan of accomplishments f o r the work. Scientific Personnel. Give the name, highest academic degree, position i n the institution,scientific experience, publications and accomplishments of the Senior Investigator ‘(the individual who will actively direct the research program) and of each reg ulm staff scientist who it i s proposed will engage inthe work. Indicate the approximate fraction of the time of each t o be devoted t o the project. Scientific personnel t o be newly employed for the p;.oject should be s o designated, and professional records given if the fraction of the time of each t o be devoted t o the project should be thesis is t o be related to the project. The number of persons of each subprofessional grade and Graduate student employees should be identified as such if their Other Financial Assistance. involving the same personnel or facilities is t o be proposed to, or received from other federal or non-university sources the extent of that assistance should be clearly stated, and the interplay of the arrangements should bs If- assistance for this or other activities Materials, Equipment and Facilities. work and justify the need for major items t o be procured. List those already available for the Travel and Other Items. Explain t h e purpose of the proposed travel, and of any other major items i n the budget. funds for attendance a t regular scientific meetings should conform with the policy of the institution in the use of its cswn funds for these purposes. Travel rates and the use of contract Budget. This should list in detail all items of cost necessary t o carry the project. It should include: alist of the individual salaries attributable t o the project, supplies and services, equipment (defined as things individually costing more than $500 which will retain their utility for more than a year),travel, comunicat ion and publication, and the indirect costs allocable explained. The budget should not include the stipend of fellows. A l l salaries chargeable t o the project should be in accord with the established policies of the institution, or, i f not, an explanation should be submitted. The basis for computing the indirect costs should be brief17

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the budget which the institution is prepared t o bear, and the amun ts requested fmm the UC, and a state m nt of any other sponsors of the project with the amounts contributed by each. ?he proposal should be signed by the Senior Investigator and endorsed by a responsible administrak iv z officer of the institution. A statement nf the part of the total amount listed in for the project, and an estimate of expenses t o be iw ur red. A current statement of its expenditures in the contract, a s brought out in the report, may be reflected in the amount f o r use of residual funds. Any diff em n ce in the scope of the work from that contemplated Tf no new funds are required the contract may be renewed without A proposal for such nznewal should state the scope of the work proposed @e radioisotopes purchase =port shall lF stall radioisotopes included in the budget at the regular price established bs the Commission, but which are purchased, or will be purchased under the current budget, ata price less than the established price by utilizing the discount authorized by an AEC Discount Certificate issued to the Contractor. For each such purchase, the report shall state the price as establi shed by the Commission, tk price paid o r to be paid using the discount, and the savings mali zed or to be realized. expiration shall cover all such purchases actually made and not previously reported. %e repod due on contract termination o r

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Tulane University of Louisiana THIS YUPPLEUENTUI m,entered b to this day of 1957, by and between the UNITED SMTES QF AMERICA ( h a r e ' d t a r ca ed the yHEaEbs, the Government and the Contractor entered into Contract No, AT- (&&1)-13C2, dated June 29, 1951, providing for a atudy of the influence of radiation Wury upon phY6fology' of serum lipids with part iw lar referenus t o tire fvlnction of the liver ; and UHXREAS, the Contract has been amended heretofore by Yodillcations Nos. WHIZBAS, the parties hereto desire t o extend the term of the contract i n order t o continue- the research activities pFeViausly undertaken, and t o effect certain other changes a8 are hereinafter more particularly described; and WH%RFdS,-'this Supplemental. Agreement is authorized by and executed under the Atomi? Energy k t of 29%; Nm, THEREFCRE, the parties hereto do mutually agree t h a t said contract is hereby modified in the follarring particulars, but in no others: 1. Ir, section 6, of Article II, the date "April 30, 1957" is deleted, and the date *April 30, 19589 is substituted them for. - 2. In subsection 1. f . of Article In,t he f oll ming Is addsd: WAS an additional consideration for said research act iv it ib s,title to the analytical ultra centrifuge and related equipment described i n subsection 2. c. of TITLE I of Appendix "A" together witk all rs?lacements and additions there to nm owned by the Government shall yest i n the Contractor a t the, end of the sixth period of performance. Section 2. of this Article Sn shall not be applicable tothe addit ional consideration referred t o Li the preceding sentence.

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3. In TITIE VI of Appendix “An, the date “ A p r i l 30, 1957” is deleted, and ths date “ April 30, 1958” I 6 substituted therefor. IN WITNESS w,t?e parties hereto have executed this Suppleraental mee ment the day a d year first above written. UNITED STATES aF AY WI CA BPt UNITED STATES ATOYIC ENWOP CW IS SION l’UUl4B UKIVWSMY OF IXIUZSIANA ACCEPTANCE BY SENIOR INVESTIUTCB I have read the foregoing Supplemental Agreement and agree t o be bound by the provisions of this document.

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Tulane University of Louisiana THIS SUPPLWENTAL AGREEMENT, entered into this -28th day of & * ' 1956, by and between the UNITED STATES OF AMERICA (here in after called the m,the Government and the Contractor entered into Contract No. A T - (bc1) - 132, dated June 29, 1951, providing for as he by the Contractor of the influence of radiatim injq upon pkViologY of serum lipids Tpith particular reference tothe function of the liver; and WHEREAS, the contract has been amended heretofore by Modifications ??os. WHEIlBlS, the parties here to desire to ertend the term of the contract i n order t o continue the research activities previously undertaken, as such extended program i s described i n TITLE V I Of Appendix "A", and to effect certain other changes as are here in after mre particularly described; and WHEREAS, t h i s Supplemental Agreement is auth4rieed by and executed under t h e Atorpic Energy Act of 19s&; NOR, THEGFORE, the parties hereto do mutua- agree that said contract i s modified in the follow hg particulars, but +n no others: The following new Section "6." is added in Article II: n6. The sixth period of performance for the research project covemd by this contract will commence on May 1, 1956, and vill end on 2. Subsection 2. a. of Article III is deleted inits entirety, and the following new subsections "1. fen and It2. 8." are added in Article 111: wf. I n consideration of the performance of the research activities described i n TITLE VI of Appendix "An, and t h e Contractorla agreenrent t o support that work in the estimated amount of Seven Thousand, Eight Hundred Dollars ($7,800.00), the Government will pay t o the Contractor for the sixth period of performance the sum of Fifteen Thousand, Four Hundred Dollars ($1S,~OO.00). "a. On or before the date …