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f itreduo ti on Mmttiot h r erganired ~ n dr updud an oxtonriva ron u ah proem aim dat tho diagaorir and aanfrol of tho- huardr pooolirr t o tho derrlopsat of .tomb onergye produaod through abaldontal or por we to radiation8 rP it tod by vnrlour rad loa ott w mterialr durlng o~cpsrlnental or proearring opentlms ar -11 a s the ohdm1to xi o it y or 1OOnlited radiation from sooh mtorlalr deposited rfthfn tho body. f'o11dng rh g hox po ~ u m rt o largo mountr of Fadietion hrvo beon deintroduatlon of wi our to dora dr8dha et iv m x,rterialr Into tho bed7 of to tenn or hr rh of radiation af todo oatsrimlr todoh p6rronaml o m be rafoly up or ad for & period of the, .ad thm oontrol of ruoh hacard8 It iamrodlotoly boopmor obriour thrt many orltiaal pbt an r of far romau raop rom h to bo r0lP.d. of' theme inJuriour affeotr La body tioruer i r hlmort oompiatoly rad lat len in3uri.r. aoofdentd h$uy t o radiatioa or rrdimotivw ~ b fia lo. baaaw ~obriour that moh problem relate t o the fundamental ashre of lit inc ; ruttor aad dana tho oaroful and 00ntIrrtl4 attention of oompoSuoh rbudie8 ham boon axroftal in tho do tard ~ t i ~ milo tho abow Mom tion ha8 boon ortromolg urof'ul in thir uwk lo thorrpoutio mam rar am as h.pd t o uue fellarlag tmtly trafrud roi u ttir tr. obi#, but u8rried out boerurs of t h o urgent doanodr o f
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It l e ebrloue that oontinued suooosi of the rerearoh P~OYM o. I ortnbll8hod and arinta1n.d by t h i r organiratlao dmandr firat of a11 tho irrrmedirto oorreatlon of H u h and ell of the abovrzentioned yerronnol with the final daatruction of - the nualew of rrr imt l sts on rhloh ruoh a I O!i-&onriro the irrdlridurl program Will detoriorrte rapidly The program8 rnro and are orgnnirod Gaily the followlng barfo oub Sf i 8 neoerorry ts dun log mthodt of aocurhtely moasurfng a d rfcndsrdSting the doa-e of rrcZttlon t o be usod ln the bio logi o al exporh.bntation lad rnaaruramnt tf the rxtsnt o f .ny huardour rad h tion rhlch be found i n a plant arm. B. X b Biologla Bffoetr a i Ilediatlon. Boorurm o f the hrom doleterleur oftoat of radiation oa t h o anima
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1. Made ef Entrmneo FOLDER LO -0t.r of t h o Biologioal 1Changor . & Hatpro of lngutior and Itohanism by rhioh They obour !
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Purily; tho part thrar yoarr tho h d i o a l 6oatian of tho Y.nhattan Lnrtriet h.8 o?g.nlrod md rup or ri rod IP or to no lr,n roar ah program .hod a t tho dlaplarlr and aontrol of thoro harardr p wdl u to tho dorrlopmont of atamib onorgy. produwdthrough aaoidsntal sxporure t o radiation8 dtt&by rrrlour -11 ar the oh do alto xi olt y or looallred radiation from moh amhrialr dopos1t.d ri thin tho body.
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It muit bo slaphadrod that this program-rauld not neaorrarily bo lb it od in lfr rpplloationr toaWo problmr alone, boaaure, an If h.r already boon 8hm, t h e foehniquor demlopod rill y$old tniormtlon of great fapar$anar, t o almrt mry brrnoh of biology and modioina. Organftmd offort again rfll ~ UOOO88fUll ydovklop additiozml n m twlo .whloh can bo u r d In tho attaok on fundmental medio*l problmr. A allghtly mor. detailed outline of the field It giwn bolm. XI Oonenl StuEioe of Radistion mnoounterod from naturally radioeotfre suhstanoer didde themselmr into tho following type mdl pb rayu, beta rap, gemma thy6 and neutrons. rather oxtel;sive knowledgo of the bio logi o al effect8 o f &rays and gamm ray8 and wq little in ion net ion on alpha and beta rays .md It 2s noosssary Co dovrlap asthodr of aouurately meaaurixg and standardiring the doeage of radiatfon t o be use kl n the blolagioal axpetlmenta= tion and neasura~ront of the extent of any hatardm6 radiation rhiah might bo found ina plant area. I. I 3, The Eiologio Wfeots of Radiation. Secauss of the knom doleteriouo of'feut of tadlation on the animal o ~ g m i s ~ p ,it beoonsr n9008ruyto determine the effeot of 00ntr0110a dosagis of the variour trper of radiatiun oa various animal speo€.ea, 10 that suoh obeerretions 0.21 bo ured in the oontrol of posslblo human eXPOIUYSe The typos of bia logi o al oif'ect porsible t o study .IO& (2) me Genetio H'fmstr aim di atl on a8 nunifeeted in tho dovolopmmrt of abnormal in did d - 1 typer from e hur gmr in tho heroditarg
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(6) Bioohadsal and Ent pati a dirturbancror rhlah u e the potonti.], ioucoe of thoro pbqriologioal abnorulltier. d m l e p a d dlreotly from ebromtion of tho .bow typo8 and mro applied t0 rtudy of tb, hrm indiridurl m workor. Tho- inolado rbudior o m (1) Bio ah daal .ad Ibuymmtla Ch.ng.8 -ah bo dotootod m d rhloh, $f mrrrurmblo, aan bo oorroeted botoro bnl.rrIb10 a g o brf abn plaae. br s plo ~of oueh ebnge would bo effootr on the rotaboli~mof eaproporphgrrlru, orarotiw of abnorrarl mbrtanoor fa tho (1) M&hodr of phyr%aal dotootian of rxb or nal rmdfatlon tho dmmlopmnt of soneltin, dinat road- iru fru ~ ont reapble of fh.
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