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TITLE: Tho LCfoets of x - irradiation on tho Urnman wschrtcn IRSTITUTIOR: tmrrs toeh. on ivor s tty 1 - lr radi rti on domoo of 10, 75, ZOO, ana 600 r of foe ts of irradiatlor on tho mbcollmlar stractsro and fmnctlon of tho tOBth Tbo to st is 1s en ort too sly rrdlosonsitl+. tlssmo. # n early lr radi rtl on off oct is tho broakbovn. of spoteatoponirl colls vblcb loads t o . st. msbjoctod t o an oloctron mie roro pk ato08porola. Tho r or p prs r ram of tho c ortho rocovory procoss, Lovovrt, thot laing of am plo to ropopolatlon of tho moni~lfororu rv or rl yoare for high doses. thoso sorpboloplcrl ovontm, it k.8 boon nog post ~ at hat it ta air tio m may alter tho local i ratio a of various onzyaes. De oxamlna blOp810s obtain06 from a fov alnmtos t o rv oral months aft or ltr adl rtl on to d of in o s tnc toro ra4 i n onrymlc local ir rt ions arcing process. oor ros olt s with thw fr r rai a tod to occur i n normal, aon-irradlatod human tostos. The mnzysos oxaminod inclod. acid phosph a t as., t hiaaino pymphosphataso, glmccno-6- phospha tam, lnosino diphosp hat as c, rr to q onic coll mriom Dark# tho bogfrninp rrnr : oiological XffOctB of Ion i xia g naaiation a t ~ o loc nl rr ,C oll a lar, ana nosan Lovol Ltooic la rgyI ro jut dombls strand DaL broaks vill bo done vitb LSIIBT ana nota cells. Tho rap air of single ana port l cala rly of doublo strand broaks will bo cap a rodr it b tho ability ,f tho Coll, a t tho maso ago, t o ropair mb lot hal denago. Laago has alrordy shorn that in synchronous darimg c(i) ana la to s than doting other staqos of t boro pli cat lon q clo. Sine. tho prograssion cosponont of Llkind-Sutton type solocular ropair ro6pon6iblo Cor tho r spal r of sublothal damago sbould also occur toa rch groator orton tat thor stag... Tho plaaarian vill bo used as a m3d.1 systos for tho stnay of stoa eo11 population kinotica, pmrticolarly rith rogard t o tho Xos6 of a if fot ~ nti at iv oi n to g city an4 th a an lsa las sochaniss(m) for tho control of u d mrk vi11 continuo along tho aaao llnos. thoroagh medical oramlnrtion, lacloding urlno analysis and l u n g counts, of ns many of thoso f o r aotomatod gradlont analysis has boon 10. l a progross. A planarian laboratory has A Study Of for nr plmtonium UOC ~ OCS with Of Dmp..ir lmgobrim ham k O n loand,