Development of Techniques and Methods for Medical Application and Environmental Health Problems - Budget and Reporting Code Ha-02-07-01 (Partial)

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TITLE Development of Techniques and Methods f o r Medical Application and Env ironmen t a 1 Hea 1t h Prob lems BUDGET AND REPORTING CODE DATE PREPARED Considerable effort has been devoted t o minimizing the variations in counting efficiency in whole body counting by Dudley, International Atomic Energy Agency; Naversten, Lund; and Genna, Massachusetts Institute of Technology. The BNL counter is the only known system with an invariant counting response t o internally deposited radio nuclides. computer and coincidence electronic circuitry is the most advanced whole body counter in existence. The BNL whole bbdy counter with i t s on-line ASSOCIATED UNIVERSITIES, INC. BROOKHAVEN NATIONAL LABORATORY Representative groups working on the same clinical studies are those of Kaye, Laurentian University of Sudbury, Canada, studying treatment o f uremic patients with vitamin D analogues t o combat osteodystrophic changes; Hioco and Bor die r, Paris, France, on effect of synthetic calc it on in on C a metabolism in osteoporosis ; and Heaney , Creighton University Medical School, on skeletal response t o growth hormone. Studies on exchangeable Na and extracellular fluid volume have been performed by Skrabal (Hammersmith) and N e l p (Univ. of Washington). trogen and hyperalimentation have been performed by McNeill and Jeejeebhoy of Toronto, and Burkinshaw and Hill of Leeds University, England. CODE WP NUMBER TASK NO. REV. NO. Work done under this task proposal has either no environmental impact o r has impacts similar to those described i n and covered by BNL's Environmental Impact 1. Capital Equipment Requirements for FY 1986. Several clinical projects within this program are dependent almost daily upon the Whole Body Counter and the Prompt Gamma Facility. It is,therefore, necessary that both these instruments operate with a minimum of down time. This can be achieved by duplicating hardware o r by acquisition of key interchangeable boards for the computer/analyzers. This would cost $15,000 for the Prompt-Gamma system and $25,000 f o r the Whole Body Counter system. There isa continued requirement for general purpose electronic equipment ($10,000) which will be utilized in various ongoing and new projects. cludes several electronic modules for nuclear spectroscopy: research amplifiers, delay and gate generators, pulse generators, analog to digital converters (ADC) ? The neutron generator project(Inelastic Scattering Experiments) requires an analyzer ($38,000) with 4 ADC input and programmable control for a high-pulsed