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Please draft a letter to Dr. Crook f o r my signature communicat ing OUT approval of the plans for Extension of the Promethium-143 Study to Cover DTPA Injections. Please notify H.E. Palmer regarding Item 2 in the Committee I am sending Julian Nielsen the attached note regarding t h e report of Walt Wilson's group on the Walla Walla project. Please assume immediate responsibifity for BNW's n e x t phase of involvement with Dr. Paulsen'a study. Subject to Paul Santilli's findings, pursue the direction suggested by the committee. Also communicate our intent promptly to Dr. Paulsen, by telephone, or if appropriate by drafting a letter(3) for my signature, I concur with the general recommendations: (I) That WQ work towards separation of 8NH f r o m the project, and ( 2 ) that in the interests of good relations with Dr. Paulsen, the U. of W. and AEC-DBM we seek acceptable interim actions for BNTV which will assist him in continuing h i s research. I believe our Pd lure to separate from the project sooner, und our prolonged participation in the work to d a t e , in effect constLtuta a n implied cod t ment to Dr. Paulsen that w e will see him through. commftment, albeit implied, without good reason. Good reasons, in my opinion, are: I do not want BNW to break that (1) Technical findings which make continuation inadvisable. (2) Aclministrative findings which clearly in a cate that - Battelle or its staff members are being subjected t o
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undue risk of financial liability or risk of damage (3) Refusal or reluctance of our s t a f f members to partiAs yet, I am not persuaded that we should not continue as I am requesting you to do in thie memo.
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Mr. Parker, Chairman of t h e Human Subjects Committee, has advised me as follows: "On the whole, the committee felt that it should not be i n the position of approving this document, as such. It fs a technical discussion of some aspects of the calibration of the University of Washington's fast neutron medical research facility, as set up for irradiation of humon testes. I n the opinion of the Committee, every item in this report could be technically correct and yet the actual exposure of human volunteer8 could be completely botched. appear, for example, to be qdte foolhardy t o conduct these experiments without making various measurements of the dose actually received by the volunteers, In discussing this point with the sponsors of the report, it was clear that these steps were intended, They are, however, n o t included i n the document. For this reason, the Cod tte e takes the but neither approves nor disapproves its publication. Please give consideration to these comments and decide if an addition should be made t o the report which describes the recommended o r presumed actual dose measurements, In any case, the report should make it clear that the correctness of the reported work does i n no way ensure the correctness of any