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Radiation Laborat or;; Be r k d ey W-7405 -Eng48 10. Person i n chnrge (Contractor ' s staff) 12. Purpose, Meed and Scqc% To perform t.?acs;. a x ! radicautcg.?a?hic studies to determine the deposition of radioactive eI.?me?$a i n v2rions par-lims or' the and i acd human body, 14. and 15. Acccr;~~iF3iL?:'311't3L ast Pear and Zxpected Resul'Gs Tkis Year 1. CzrrieT-free Fh15~ has Seen studied at 2, 5, 24 and 48 ho crs after ix tr zve no ix aC,iibis:Fzkion and fourld t o be rapidly excretedc venous and inLramuscular edm in is tr z tion. blood cells car! be tagged quite vel1 in that the radjA.sotope rem in s in the cells for ai extJended priod of time, considerable de pcs it ion and prot rect ed retention in - the skeleton. ttcarrier-fxett level ar,d were found t o behave simih ? ly with other rare 2nd 'criior beAi-Sng rats a t 2 and 4 hours and 1, 4 and 7 days after i n t r a - venous ahini st rati o n was found t o behave ina manner somexhat similar to that of plutonium i n that high uptake and prolonged retention by the skeleton was observede have been per fon icd et a &hour interval following intravenous a chin is tra - It was noted that in the rat red This radioelement may have 29Carrier - free SCL6 has been studied at1 and 16 days, The time intervals ranged from 1to 64 days, 6,Studies with carri2r - free bismuth have been performed with normal A group or" rats given Xp237 were sacrificed after 64 days and it Pre l knin arge x per ln ents on the distribution of carrier - free Mo99 This radioeleinent appears t o be very mp id lp eliminated from the 3:- See cspy of detailed description tralsamitted t o Division o f Biology.and Medicine,
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Tracw and Radioauthographic Studies(Cmt in u ed) Accovp;isrmeins Last Year and Exp c ted Results This Yea;. (Conti r 9.- A study of the shift of pot as siu ii aild so dim in the rat following tx ac crs, Ample eaidence was secured - that both electrolytes show vasiatAons in concentration f oll ming h - radiation an:! the in crea s in elect r clf les i:;c or related with the r akio sensitivity of thetis s a2ad NaZ2 and K@, $3 were used as Anong the new problems tobe s5udied arc im lude d bag - term studies with neptuniun, a rare earth. technetium, r-heniu?l and bromine, to explore - their eflec-L Oil the thyroid are References ad the literature both indicate that thesr; elements 1% i s planned t o expand the radio1-8 Plant and Equipmr,t Costs All Equipment purchased ?G: Fadl ation Labor at cry Equipment Pcol, Years Ycar s Years + See copy of Zetel2d6e script ion tz-ansmittcd to Ci vision of Biology and Medicine,