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NOTICE OF RESEARCH PROJECT PUBLICATION BY AEC SWTHSONIAN INSTITUTION UNITED STATES ATOMIC ENERGY COMMISSION NANE AND ADDRESS OF XNSTXTUTTON: Please state also the Division, IhpaTtment, or Prof esa ion d School (bodied, 8r.duate, or other)rith which this project ahould be i dont if ie & . University of Rochestert Rochester, New Park TITLE oF PRoJECT A continuing program of medical examinations of the eight survivors of the Los Alamos radiation incidents of 1945 and 1946 .WWL (not in clu d in RR tn dun te students) engaped o n the project,urd fraction of ann - year devoted to the pm j ect .WYMIIRY OF PmPOSED HOW - (30 - 300 words. Omit confident ipl data.) Summaries nre exchen6ed with p vern ment and private e qc nci esa up port in E research,are supplied to invest ips tors upon request,and may be published in AEC docuI!ow many p radu ate student men-years? for awdy ; prop oae d PROCEWRE; TEST OBJECI'S ~d AGUYTS; ' urd RESULTS ID ' NO SUMMARY HAS. BEEN PROVIDED FOR USE OF SCIENCE INFORMATION EXCHANGE I Period for this NRP 1
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PUBLIC HEALTH SERVICE lion Exchanpo. XALTH, EDUCATION, AND WELFARE rNot for publication or publication NOTICE OF RESEARCH PROJECT'& TITLE OF PROJECT WHICH THIS PROJECT SHOULD B E IDENTIFIED SIGNATURE OF PRINCIPAL INVESTIGATOR GIVE NAMES DEPARTMENTS AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER PROFESSIONAL PERSONNEL 'ENGAGED ON THE PROJECT. .I&.Heselrnann,__-I-M.D. Principal Investigator, Dept. of Fkdiology NAME AND ADDRESS O F APPLICANT INSTITUTION University o f Rochester School of Medicine and Dentis.t;ry, Rochester, N.Y. bio-rcioncer and are forwarded to investigaiorr who request such information. Your wmrnary is lo ba used for these P w P O ~ s . In the Science information Exchange summaries of work in progress are exchanged with government and private egencies supporting research i{ the Several populations treated with x-rays i n infancy and childhood are being kept under surveillance many years after exposure. The incidencq exceedingly high and a definite dose response has been shown t o occur' a in both thyroid and extrathyroid neoplasms, Although data on tumor incidence has been collected in the past by mail questionnaire, we are now examining several subgroups with an especially high risk of developing thyroid neoplasms. I n one subgroup, the projected incidence of thyroid nodularity i s almost one in three. When malignancy i s suspected, surgery i s recommended and, in other cases, the nodules are either treated with thyroid hormdne o r kept under careful observation. Special tests of thyroid function are being undertaken i n persons with thyroid nodules and operative tissue from one patient has been grown in tissue culture. of neoplasms, particularly those arising in the thyroid gland, isP. Proj. No. Pcriod Amount