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*T&ephom conversation 12-16-47 be been Dr. Albert 3. Holland, Jr, and Dr. Cello of Dr, C*- This i s Dr, cello down i n Birmingham, Dr. Earl Branden and I have a patient who has a carcinoma of the thyroid which is in opr able and has eroded I wonder i f there is any may possible of getting some radioactive ?ks&mpxx Dr. H, - I would l i k e t o be able to help you very much. However, have you used that the applications and channels are already s e t up? No xm Wve not. could probably help, By that 'I &an, have you ordered any before so This has been the first patient that we felt that it thatts o m of our diff icu lees, as you we can allocate them we have to get a great my legal forms drawn up and b e absolutely certain that the proper radiation detection instrwaents axe installed and available for measuring adninistered dosage and md.torbg this patient, because that would probably take a month to6 weeks t o do, Emver, WB might be able to get sonebody down there i n Birminghan who has received the material and see what wa can work out. hold the wire about 2 minutes I w i l l rind out who i s down there tha-k we might be able t o work o u t some arrangemsnt with. ..,....... On the first applioation request f o r isotopes, before I am afraid it wouldn't be feasible during the lifetime of If you xi11 just Docto r, In talking with the people inthe Isotopes Div.I haven't been able t o give you very muoh help. As a mtter of fa&, &inking it over clinically, if this man has been irradiated heavily, It mah aid we can't accomplish much by giving him firth- therapy d t h iadine because it takes a considerable period of time and w i l l only incmase the radiation effect; and it d.11 take some arne before you w i l l get adequate uptake i n the thyroid. Particularly, if this has eroded through &to t h e trachea. realize the acuteness of %e situation but i f it has eroded thou & t o the trachea, I'm afraid the prognosis isntt very hopeful even at best. We think, however, that it i s some type of ulcerative emsion and he has never had a hemorrhage but i s som sort o f an affair abd he probably loses i n the neighborhood o f 100 or 200 cc of blood a day. This has been going on f o r a number of weeks That is very possible if it is om of the lO-IS~/tfryroidmalignancies *ich :as an affinity f o r the iodine, They don't all manifest that, as you knopo, Iwould $uggest, i f it i s within tb patientts means, that WB perhaps could refer him to one of the institutions where$'mtope programs -established, t o have you write into the Isotopes Division here and get all the necessary infomation and forms executed so that you might ha,= the advantage of this in just a matter ofa day or tmo. Bad, forpu and your colleagues i n the &turn, wetd be glad Then, when you call u? we canexpedite a request for you Tell, we w i l l Q that. Of course we would probably need a radiologist
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arYH. ayes, or prefem ly, are you associRted with the University there? I personally am not but my colleague .... . I think if you write t o the Isotopes Division bre i n Oak Ridge, they can firnish you w i t h the necessary idormation and be of further service I'm a f r a i d there is nobody. ??e have @ne over the Birmingham, New Orleans and Atlanta area and really the best we can offer you i s l&morial Hospital inNew York, hi&i s considerable distance away. mere is 220 one over &ere. Vanderbilt has since lee. not ?miliar with human administmeon, dosage o r aoything else. afraid I can't give you much help other than sending him that dist we. %e man .~llhomas using soae active materialsat They do not have an active isotopes pmgm thereThere are som3 people i n Atlanta who are using Carbon 14 but are I think as I mcall it they were using radioactive gold. any o f the n;101~8so f *he msp off ha&. I ' certainly would like to help you and the patient but I'm afraid in this in s tame it probably muld not be. '&at you might do, of course, is t o suggest to the patient t h a t he go,%- Hanorial forR matter of 2or3 weeks o f therapy and then in the in te - w establish your own relationship with. US. Then he probably would want to return hame and you might contime treatneot if you think he is going t o be d t h us that long. ......,...,,..??9.9k@mc~m locally has not mstastasized, He has had it now fora matter of 6 to 8 years and has had 2tD tal thymi dect des In that event *en, he might go up there just on the basis of a short course o f therapy axxi then mturn back t o your care. write us here i n Oak Ridge, P.O. Box E, I am w e that we can supply you mith sane information and instructions as t o how h x p p the law requires that we license an lso to a e user. In the meantime if pu will I certainly thank you f o r your information and time, Your wlccane, I ' m sure. Am sorry me couldn't be of =ore service t0 you.